NUMBER FIVE
The Gatling Laser from Fallout 3

Gotta start with this one.
Doing this list I had a long fight over which I should feature, the Fat Man or this baby here, but ended up with this for one reason: the Fat Man’s unique version is called “Expiremental MIRV”, while this one’s unique version is called “Vengeance”. Vengeance sounds a lot more bad ass than anything with EXPIREMENTAL in it…
Capable of doing a lot of damage in a short time span (103 damage value, 176 with Vengeance) with the huge 240 round clip, equipping one of these simply dropped any Enclave Warrior or Super Mutant on their knees when I rushed into the glorious battle in the ruins of the Capital. And hey, what’s cooler than lasers?